Endotoxin, a novel biomarker for the rapid risk assessment of faecal contamination of coastal and transitional waters
| Autor: | Christian R. Good, Alistair White, Joao Brandao, Simon Jackson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of Water and Health, Vol 22, Iss 6, Pp 1044-1052 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1477-8920 1996-7829 |
| DOI: | 10.2166/wh.2024.122 |
| Popis: | Current methods for testing water for faecal contamination rely on the culture of faecal indicator bacteria (FIB; Escherichia coli and Enterococci) that take 24–48 h, which leads to delays in taking proactive measures and poses a risk to public health. More rapid methods are therefore required. Here, we have tested a rapid, portable assay (Bacterisk) that detects the bacterial biomarker endotoxin in 30 min to quantify the bacterial biomass present, to evaluate 159 coastal water samples and to compare the results with the traditional culture of FIB. There was a significant correlation between the Bacterisk data given in endotoxin risk (ER) units and FIB culture that could accurately distinguish between poor and sufficient or good quality bathing water using the EU bathing directive values. Receiver operating characteristic analysis was used to determine the optimal ER threshold for coastal water samples, and the area under the curve was 0.9176 with a p-value of |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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