Antithrombotic therapy at discharge and prognosis in patients with chronic coronary syndrome and atrial fibrillation who underwent PCI: a real-world study

Autor: Yimeng Wang, Yanmin Yang, Lulu Wang, Han Zhang, Jiang-shan Tan, Yuyuan Shu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Thrombosis Journal, Vol 22, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1477-9560
DOI: 10.1186/s12959-024-00628-1
Popis: Abstract Background This study aimed to describe the status of antithrombotic therapy at discharge and prognosis in patients with atrial fibrillation (AF) and chronic coronary syndrome (CCS) who underwent percutaneous coronary intervention (PCI). Methods This was an observational, prospective study. The primary endpoint was major adverse cardiovascular events (MACE), including all-cause death, myocardial infarction, stroke/transient ischemic attach (TIA), systemic embolism or ischemia-driven revascularization. Bleeding events were collected according to the Thrombolysis in Myocardial Infarction (TIMI) criteria. Results Between 2017 and 2019, a cohort of 516 patients (mean age 66, [SD 9], of whom 18.4% were female) with AF and CCS who underwent PCI were evaluated, with a median followed-up time of 36 months (Interquartile range: 22–45). MACE events occurred in 13.0% of the patients, while the TIMI bleeding events were observed in 17.4%. Utilization of TAT (triple antithrombotic therapy) (P
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