| Autor: |
Yuanzheng Cheng, Zhuofan Gui, Ran Tao, You Wang, Shaolin Zhu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Green Synthesis and Catalysis, Vol 3, Iss 4, Pp 377-379 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-5549 |
| DOI: |
10.1016/j.gresc.2022.03.009 |
| Popis: |
An enantioselective NiH-catalyzed hydroalkynylation of α,β-unsaturated amides is reported. A wide range of α,β-unsaturated amides and bromoalkynes are suitable substrates for this reaction, which proceeds under mild conditions, allowing access to a variety of enantioenriched chiral β-alkynyl amides. β,γ-Unsaturated amides can also be used as substrates and undergo the β-selective hydroalkynylation with a slightly lower enantiomeric excess. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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