| Autor: |
Murat Bayantemur, Emrah Aksakal, Oktay Gulcu, Gökhan Ceyhun, Engin Şebin, Oguzhan Ekrem Turan, Ali Korkmaz, Mustafa Öztürk, Kamuran Kalkan |
| Jazyk: |
English<br />Turkish |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Sakarya Tıp Dergisi, Vol 10, Iss 4, Pp 623-628 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2146-409X |
| DOI: |
10.31832/smj.767212 |
| Popis: |
Objective: Adropin is associated with energy balance in tissues and organs. The SYNTAX score (SS) is used to determine the severity of ST-segment elevation myocardial infarction (STEMI). The aim of this study was to determine the relationship between serum adropin levels and disease severity in STEMI patients. Materials and Methods: Eighty-nine patients who underwent coronary angiography (CAG) for STEMI were included in the study. The STEMI patients were divided into two subgroups: Group 1(SS < 22) and Group 2 (SS ≥ 23). 43 patients who underwent CAG and had normal coronary arteries were included in the study as a control group. Results: Groups 1 and 2 included more male participants than the control group (89.7% and 74.2% vs. 34.9%, respectively, p < 0.001). The smoking rate was higher in Groups 1 and 2 than in the control group (55.1% and 34.4% vs. 11.6%, respectively, p≤0.001). Serum adropin levels were lower in Group 1 than in the control group (147.3 ± 149.2 mg/L and 228.1 ± 253.3 ng/L, p = 0.03). Serum adropin levels were the lowest in Group 2 (87.8 ± 23.2 ng/L, 147.3 ± 149.2 ng/L, and 228.1 ± 253.3 ng/L, p = 0.004). Serum adropin levels were also negatively correlated with SS (r = -0.33, p = 0.002). Conclusion: Serum adropin levels decreased more in STEMI patients than in those without coronary artery disease (CAD). In addition, serum adropin levels decreased with increasing SS;this indicates the severity of CAD. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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