The Effect of Vitamin D Deficiency on Overgrowth of Uterine Fibroids: A Blinded Randomized Clinical Tria

Autor: Fatemeh Davari Tanha, Elham Feizabad, Maryam Vasheghani Farahani, Hoora Amuzegar, Behnaz Moradi, Saghar Samimi Sadeh
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Fertility and Sterility, Vol 15, Iss 2, Pp 95-100 (2021)
Druh dokumentu: article
ISSN: 2008-076X
2008-0778
DOI: 10.22074/ijfs.2020.134567
Popis: Background: To evaluate the effects of vitamin D (vitD) supplement on uterine fibroid growth.Materials and Methods: A randomized blinded clinical trial was conducted at a tertiary university-based hospitalfrom August 2017 to September 2018. Totally, 204 women were enrolled into the study. They had at least one uterinefibroid >10 mm on transvaginal ultrasound and their vitD level was insufficient (i.e. 20-30 ng/ml). The interventiongroup was treated with vitD 50000 U supplements for two months. After 2 months, ultrasound screening and vitDlevel measurement was done in both groups.Results: At first, the mean serum vitD levels in intervention and control group were 23.62 and 23.20 ng/ml, respectively.After 8 weeks, the mean serum vitD levels in the control and intervention group were 22.72 and 28.56 ng/mlrespectively (p
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