The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer

Autor: Stojanovic-Rundic Suzana, Marinkovic Mladen, Cavic Milena, Karapandzic Vesna Plesinac, Gavrilovic Dusica, Jankovic Radmila, de Voer Richarda M., Castellvi-Bel Sergi, Krivokapic Zoran
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Radiology and Oncology, Vol 55, Iss 4, Pp 449-458 (2021)
Druh dokumentu: article
ISSN: 1581-3207
DOI: 10.2478/raon-2021-0039
Popis: Historically, the treatment of choice for anal cancer had been abdominoperineal resection (APR). Radical radiotherapy with concurrent 5-fluorouracil plus mitomycin C chemotherapy was later established as standard therapy, although with a failure rate of 20–30%. The aim of this study was to evaluate the outcomes after radical chemoradiotherapy (CRT), prognostic and predictive factors and patterns of failure.
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