Case Series: Acute Hemorrhagic Encephalomyelitis After SARS-CoV-2 Vaccination

Autor: Mihai Ancau, Friederike Liesche-Starnecker, Johanna Niederschweiberer, Sandro M. Krieg, Claus Zimmer, Charlotte Lingg, Daniela Kumpfmüller, Benno Ikenberg, Markus Ploner, Bernhard Hemmer, Silke Wunderlich, Mark Mühlau, Benjamin Knier
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Neurology, Vol 12 (2022)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2021.820049
Popis: We present three cases fulfilling diagnostic criteria of hemorrhagic variants of acute disseminated encephalomyelitis (acute hemorrhagic encephalomyelitis, AHEM) occurring within 9 days after the first shot of ChAdOx1 nCoV-19. AHEM was diagnosed using magnetic resonance imaging, cerebrospinal fluid analysis and brain biopsy in one case. The close temporal association with the vaccination, the immune-related nature of the disease as well as the lack of other canonical precipitating factors suggested that AHEM was a vaccine-related adverse effect. We believe that AHEM might reflect a novel COVID-19 vaccine-related adverse event for which physicians should be vigilant and sensitized.
Databáze: Directory of Open Access Journals