Racial and Ethnic Minorities Have a Lower Prevalence of Airflow Obstruction than Non-Hispanic Whites

Autor: Akshay Sood, Hans Petersen, Congjian Liu, Orrin Myers, Xin Wang Shore, Bobbi A. Gore, Rodrigo Vazquez-Guillamet, Linda S. Cook, Paula Meek, Yohannes Tesfaigzi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: COPD, Vol 19, Iss 1, Pp 61-68 (2022)
Druh dokumentu: article
ISSN: 1541-2555
1541-2563
15412555
DOI: 10.1080/15412555.2022.2029384
Popis: Racial and ethnic disparities in chronic obstructive pulmonary disease (COPD) are not well-studied. Our objective was to examine differences in limited COPD-related outcomes between three minority groups—African Americans (AAs), Hispanics, and American Indians (AIs) versus non-Hispanic Whites (NHWs), as the referent group, in separate cohorts. Separate cross-sectional evaluations were performed of three US-based cohorts of subjects at risk for COPD: COPDGene Study with 6,884 NHW and 3,416 AA smokers; Lovelace Smokers’ Cohort with 1,598 NHW and 378 Hispanic smokers; and Mining Dust Exposure in the United States Cohort with 2,115 NHW, 2,682 Hispanic, and 2,467 AI miners. Prebronchodilator spirometry tests were performed at baseline visits using standard criteria. The primary outcome was the prevalence of airflow obstruction. Secondary outcomes were self-reported physician diagnosis of COPD, chronic bronchitis, and modified Medical Research Council dyspnea score. All minority groups had a lower prevalence of airflow obstruction than NHWs (adjusted ORs varied from 0.29 in AIs to 0.85 in AAs; p
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