Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis
| Autor: | Azael Torales-Cardeña, Isaí Martínez-Torres, Sandra Rodríguez-Martínez, Fernando Gómez-Chávez, Juan C. Cancino-Díaz, Ernesto A. Vázquez-Sánchez, Mario E. Cancino-Díaz |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Mediators of Inflammation, Vol 2015 (2015) |
| Druh dokumentu: | article |
| ISSN: | 0962-9351 1466-1861 |
| DOI: | 10.1155/2015/607363 |
| Popis: | Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor “hypoxia-inducible factor 1-alpha” (HIF-1α) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1α in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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