Anti-oxidative stress properties by Lactiplantibacillus plantarum SCS3 in streptozotocin-induced diabetic mice

Autor:	Xiao Meng, Shukun Liu, Qiuyan Liu, Ying Zhang, Lin Jing, Xinyi Huang, Jiayi Sun, Lu Ye
Jazyk:	English<br />Spanish; Castilian
Rok vydání:	2022
Předmět:	Lactiplantibacillus plantarum SCS3 type 2 diabetes oxidative stress improvement enzyme linked immunosorbent assay experimental techniques Nutrition. Foods and food supply TX341-641 Food processing and manufacture TP368-456
Zdroj:	CyTA - Journal of Food, Vol 20, Iss 1, Pp 297-304 (2022)
Druh dokumentu:	article
ISSN:	19476337 1947-6345 1947-6337
DOI:	10.1080/19476337.2022.2136759
Popis:	This study investigated the ability of Lactiplantibacillus plantarum SCS3 (L. plantarum SCS3) to alleviate oxidative stress in diabetic mice. Diabetic mouse model was established by administering 50 mg/kg (bodyweight) of streptozocin for 5 days. We then applied 0.5 mL of 1.0 × 1010 CFU/mL L. plantarum SCS3 cell suspension (TGa group), its intracellular contents (TGb group), or boiled intracellular contents (TGc group) to mice for ten weeks. Compared with the model group (MG), weight loss and hyperglycemia were most effectively ameliorated in the TGc group compared to the other treatment groups; based on the enzyme linked immunosorbent assay, levels of insulin and glycosylated hemoglobin were improved; the reactive oxygen species level decreased, while superoxide dismutase, catalase, and glutathione levels in the TGc mice increased significantly (P
Databáze:	Directory of Open Access Journals
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