Assessment of vitamin K levels in women with intrahepatic cholestasis of pregnancy

Autor:	Maria Cemortan, Irina Sagaidac, Olga Cernetchi
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Intrahepatic cholestasis of pregnancy Obstetric cholestasis ICP Pregnancy Gynecology and obstetrics RG1-991
Zdroj:	BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-6 (2022)
Druh dokumentu:	article
ISSN:	1471-2393 41399447
DOI:	10.1186/s12884-022-04875-w
Popis:	Abstract Intrahepatic cholestasis of pregnancy is a disorder characterized by pruritus and elevated liver function tests and bile acids. Poor vitamin absorption and, as a result, hypovitaminosis K can occur as a result of the pathology. Given the known effects of vitamin K, the authors considered that hypovitaminosis K could increase the risk of coagulopathic hemorrhage in pregnant women. The study revealed that 59.2% of women with intrahepatic cholestasis of pregnancy were diagnosed with hypovitaminosis K; however, 98.6% of women had normal coagulogram indices. Thus, coagulogram markers are more likely to indicate vitamin K activity than its actual level.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3b70b7f256ce41399447b699fc74597e Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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