| Autor: |
Faniry H. Razafindrazaka, Pavlo Yevtushenko, Konstantin Poelke, Konrad Polthier, Leonid Goubergrits |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Royal Society Open Science, Vol 6, Iss 2 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2054-5703 |
| DOI: |
10.1098/rsos.181970 |
| Popis: |
A discrete boundary-sensitive Hodge decomposition is proposed as a central tool for the analysis of wall shear stress (WSS) vector fields in aortic blood flows. The method is based on novel results for the smooth and discrete Hodge–Morrey–Friedrichs decomposition on manifolds with boundary and subdivides the WSS vector field into five components: gradient (curl-free), co-gradient (divergence-free) and three harmonic fields induced from the boundary, which are called the centre, Neumann and Dirichlet fields. First, an analysis of WSS in several simulated simplified phantom geometries (duct and idealized aorta) was performed in order to understand the nature of the five components. It was shown that the decomposition is able to distinguish harmonic blood flow arising from the inlet from harmonic circulations induced by the interior topology of the geometry. Finally, a comparative analysis of 11 patients with coarctation of the aorta (CoA) before and after treatment as well as 10 control patients was done. The study shows a significant difference between the CoA patients before and after the treatment, and the healthy controls. This means a global difference between aortic shapes of diseased and healthy subjects, thus leading to a new type of WSS-based analysis and classification of pathological and physiological blood flow. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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