Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

Autor: Yong-Bin Wang, Sheng-Cai Zheng, Yu-Mei Hu, Bin Tan
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms15489
Popis: Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality.
Databáze: Directory of Open Access Journals