Alteration of Plasma Amino Acid Concentrations in Iranian Children with COVID-19

Autor: Sedigheh Shams, Aileen Azari-Yam, Moeinadin Safavi, Zahra Zamani, Maryam Sotoudeh-Anvari, Meisam Sharifzadeh Ekbatani, Mohammad-Taghi Haghi-Ashtiani, Fatemeh Mozafari, Bahareh Yaghmaie, Leila Shafeghat
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Pediatrics, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 1687-9759
DOI: 10.1155/2022/9390327
Popis: COVID-19 is an acute viral disease that has so far infected more than 200 million and killed more than four million worldwide. It affects the immune system and other organs. Here, we investigated the level of free plasma amino acids in COVID-19 patients and compared them with non-COVID-19 subjects. We also compared amino acids levels in critically ill patients admitted to the intensive care unit (ICU) with non-ICU patients and expired and recovered patients. Twenty-six COVID-19 patients and 32 non-COVID-19 subjects were included in the study. The mean of glutamic acid, serine, glycine, threonine, phenylalanine, leucine, lysine, alanine, arginine, aspartic acid, and ornithine was significantly higher in cases than controls. In addition, the mean of glutamine was significantly lower in patients than controls (443.89±254.31 vs. 651.73±107.38, PV
Databáze: Directory of Open Access Journals