| Autor: |
Evanizio Roque de Arruda Junior, MD, PhD, Heloisa Ramos Lacerda, MD, PhD, Libia Cristina Rocha Vilela Moura, MD, MSc, Maria de Fatima Pessoa Militão de Albuquerque, MD, PhD, Democrito de Barros Miranda Filho, MD, PhD, George Tadeu Nunes Diniz, MSc, Valeria Maria Gonçalves de Albuquerque, MD, MSc, Josefina Cláudia Zirpoli Amaral, MD, MSc, Ricardo Alencar de Arraes Ximenes, MD, PhD, Verônica Soares Monteiro, MD, MSc |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Brazilian Journal of Infectious Diseases, Vol 14, Iss 3, Pp 281-287 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
1413-8670 |
| DOI: |
10.1016/S1413-8670(10)70057-X |
| Popis: |
Introduction: Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy. Objective: Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy. Method: Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension. Results: Of 958 patients, 245 (25.6%) had hypertension (cases), 325 (33.9%) had prehypertension, and 388 (40.5%) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91- 4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm3 were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension. Conclusion: Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet. Keywords: HIV/AIDS, hypertension, antiretroviral therapy, cardiovascular risk |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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