HPLC Quantification of Cytotoxic Compounds from Aspergillus niger
| Autor: | Paula Karina S. Uchoa, Leandro Bezerra de Lima, Antonia T. A. Pimenta, Maria da Conceição F. de Oliveira, Jair Mafezoli, Mary Anne S. Lima |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Chemistry, Vol 2017 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2090-9063 2090-9071 |
| DOI: | 10.1155/2017/6969358 |
| Popis: | A high-performance liquid chromatography method was developed and validated for the quantification of the cytotoxic compounds produced by a marine strain of Aspergillus niger. The fungus was grown in malt peptone dextrose (MPD), potato dextrose yeast (PDY), and mannitol peptone yeast (MnPY) media during 7, 14, 21, and 28 days, and the natural products were identified by standard compounds. The validation parameters obtained were selectivity, linearity (coefficient of correlation > 0.99), precision (relative standard deviation below 5%), and accuracy (recovery > 96). |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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