Study the effect of the mixture of alcoholic extract of Peganum harmala seeds & Pericarp of Punica granutum on viability of protoscolices of Echinococcus granulosus in vitro and in vivo

Autor: Fawzia Ahmed AL-Shanawi, Noor Nihad Baker
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: مجلة مركز بحوث التقنيات الاحيائية, Vol 7, Iss 2 (2013)
Druh dokumentu: article
ISSN: 1815-1140
2708-1370
DOI: 10.24126/jobrc.2013.7.2.265
Popis: This study included the preparation of the mixture of alcoholic extracts of Peganum harmala seeds and Pericarp of Punica granutum at concentration (1+40), (1.5+45), (2+50) mgml. To study the influence of the mixture of alcoholic extracts of P. harmala and P. granutum on viability of the protoscolices of Echinococcus granulosus In vitro (In tubes), and In vivo (In albaino white mice injected intraperitoneal with protoscolices). In vitro experiment revealed complete inactivation of protoscolices (death) with concentration (2+ 50) mg/ ml after 30 minute. In vivo a significant reduction in weight of liver and spleen occurred in treated groups in comparison to control (untreated) infected group.
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