| Autor: |
Masoumeh Seghatoleslam, Fatemeh Alipour, Reihaneh Shafieian, Zahra Hassanzadeh, Mohammad Amin Edalatmanesh, Hamid Reza Sadeghnia, Mahmoud Hosseini |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Journal of Traditional and Complementary Medicine, Vol 6, Iss 3, Pp 262-268 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2225-4110 |
| DOI: |
10.1016/j.jtcme.2015.06.003 |
| Popis: |
Nigella sativa (NS) has been suggested to have neuroprotective and anti-seizures properties. The aim of current study was to investigate the effects of NS hydro-alcoholic extract on neural damage after pentylenetetrazole (PTZ) – induced repeated seizures. The rats were divided into five groups: (1) control (saline), (2) PTZ (50 mg/kg, i.p.), (3–5) PTZ-NS 100, PTZ-NS 200 and PTZ-NS 400 (100, 200 and 400 mg/kg of NS extract respectively, 30 min prior to each PTZ injection on 5 consecutive days). The passive avoidance (PA) test was done and the brains were then removed for histological measurements. The PTZ-NS 100, PTZ-NS 200 and PTZ-NS 400 groups had lower seizure scores than PTZ group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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