| Autor: |
Matías Capurso, Gabriel Radivoy, Fabiana Nador, Viviana Dorn |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Chemistry Proceedings, Vol 12, Iss 1, p 4 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2673-4583 |
| DOI: |
10.3390/ecsoc-26-13588 |
| Popis: |
A recently published article by our research group demonstrated that the hydrothiolation of activated alkynes is a successful way to functionalize thiols bearing catechols. The reaction was promoted by the CuNPs/TiO2 nanocatalyst and was regio- and stereoselective towards the anti-Markovnikov Z-vinyl sulfide with good to excellent yields (47–97%). The scope of the reaction was evaluated and, based on experimental observations, the reaction mechanism was investigated through DFT studies. Theoretical results and experimental data were consistent with a reaction mechanism based on a copper-catalyzed anti-Markovnikov hydrothiolation process that favors the formation of the Z-vinyl sulfide. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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