What matters most to patients with multiple myeloma? A Pan-European patient preference study

Autor: Rosanne Janssens, Tamika Lang, Ana Vallejo, Jayne Galinsky, Kate Morgan, Ananda Plate, Chris De Ronne, Margaux Verschueren, Elise Schoefs, Anneleen Vanhellemont, Michel Delforge, Fredrik Schjesvold, Elena Cabezudo, Martina Vandebroek, Hilde Stevens, Steven Simoens, Isabelle Huys
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Oncology, Vol 12 (2022)
Druh dokumentu: article
ISSN: 2234-943X
DOI: 10.3389/fonc.2022.1027353
Popis: IntroductionGiven the rapid increase in novel treatments for patients with multiple myeloma (MM), this patient preference study aimed to establish which treatment attributes matter most to MM patients and evaluate discrete choice experiment (DCE) and swing weighting (SW) as two elicitation methods for quantifying patients’ preferences.MethodsA survey incorporating DCE and SW was disseminated among European MM patients. The survey included attributes and levels informed by a previous qualitative study with 24 MM patients. Latent class and mixed logit models were used to estimate the DCE attribute weights and descriptive analyses were performed to derive SW weights. MM patients and patient organisations provided extensive feedback during survey development.Results393 MM patients across 21 countries completed the survey (Myears since diagnosis=6; Mprevious therapies=3). Significant differences (p
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