One‐year survival after out‐of‐ hospital cardiac arrest: Sex‐based survival analysis in a Canadian population

Autor: Emad Awad, Christopher B. Fordyce, Brian Grunau, Jim Christenson, Jennie Helmer, Karin Humphries
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of the American College of Emergency Physicians Open, Vol 4, Iss 3, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2688-1152
DOI: 10.1002/emp2.12957
Popis: Abstract Objective We investigated sex differences in 1‐year survival in a cohort of patients who survived out‐of‐hospital cardiac arrest (OHCA) to hospital discharge. We hypothesized that female sex is associated with higher 1‐year posthospital discharge survival. Methods A retrospective analysis of linked data (2011–2017) from clinical databases in British Columbia (BC) was conducted. We used Kaplan–Meier curves, stratified by sex, to display survival up to 1‐year, and the log‐rank test to test for significant sex differences. This was followed by multivariable Cox proportional hazards analysis to investigate the association between sex and 1‐year mortality. The multivariable analysis adjusted for variables known to be associated with survival, including variables related to OHCA characteristics, comorbidities, medical diagnoses, and in‐hospital interventions. Results We included 1278 hospital‐discharge survivors; 284 (22.2%) were female. Females had a lower proportion of OHCA occurring in public locations (25.7% vs. 44.0%, P
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