| Autor: |
Rachelle Buchbinder, Bethan Richards, Lyn March, Catherine L Hill, Rachel Black, Marissa Lassere, Joanna Tieu, Susan Lester, Huai Leng Pisaniello, Oscar Russell, Claire Barrett, Samuel L Whittle |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
RMD Open, Vol 9, Iss 3 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2056-5933 |
| DOI: |
10.1136/rmdopen-2022-002962 |
| Popis: |
Objective To determine distinct trajectories of self-reported pain-related health status in rheumatoid arthritis (RA), their relationship with sociodemographic factors and medication use.Methods 988 Australian Rheumatology Association Database participants with RA (71% female, mean age 54 years, mean disease duration 2.3 years) were included. Distinct multi-trajectories over 15-year follow-up for five different self-reported pain-related health outcome measures (Health Assessment Questionnaire Disability Index, visual analogue scores for pain, arthritis, global health and the Assessment of Quality of Life utility index) were identified using latent variable discrete mixture modelling. Random effects models were used to determine associations with medication use and biologic therapy modification during follow-up.Results Four, approximately equally sized, pain/health status groups were identified, ranging from ‘better’ to ‘poorer’, within which changes over time were relatively small. Important determinants of those with poorer pain/health status included female gender, obesity, smoking, socioeconomic indicators and comorbidities. While biologic therapy use was similar between groups during follow-up, biologic therapy modifications (plinear |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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