| Autor: |
Alpana Mohta, Asha Nyati, Achala Mohta, Bhikam C Ghiya, Rajesh D Mehta, Vanita Kumar |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Indian Dermatology Online Journal, Vol 14, Iss 2, Pp 207-212 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2229-5178 |
| DOI: |
10.4103/idoj.idoj_449_22 |
| Popis: |
Background: Owing to the myriad clinical presentations of COVID-19 vaccine-induced adverse events, clinicopathological correlation is the key to understanding the underlying pathophysiology of these reactions. However, there is still a dearth of such systematic studies across a wide spectrum of vaccine reactions. Aim and Objectives: This study provides a clinical and histopathological correlation of COVID-19 vaccine-induced mucocutaneous reactions. Materials and Methods: The study population included all the individuals developing any form of self-reported mucocutaneous adverse events within 4 weeks of receiving the COVID-19 vaccine. The clinical and histopathological features were recorded. Results: A total of 126 cases were identified. Seven histopathological patterns were recognized. The most common histopathological feature was spongiotic dermatitis, seen in all the patients with “vaccine-related eruption of papules and plaques” (VREPP). Other patterns included lichenoid or interface dermatitis, dermal hypersensitivity reaction, leukocytoclastic vasculitis, subepidermal blistering, psoriasiform hyperplasia, and dermal granulomatous reaction. Conclusion: Owing to such myriad clinical presentations, utilizing a histopathological classification could ease categorizing the vaccine-induced mucocutaneous eruptions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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