Neopterin Determinations in Tuberculous Bone Infections

Autor: Peters K. M., Schweitzer K., Zimmermann S., Zilkens K. W.
Jazyk: angličtina
Rok vydání: 1994
Předmět:
Zdroj: Pteridines, Vol 5, Iss 2, Pp 61-64 (1994)
Druh dokumentu: article
ISSN: 0933-4807
2195-4720
DOI: 10.1515/pteridines.1994.5.2.61
Popis: In patients with tuberculous chest infections caused by intracellular Mycobacteria elevated serum neopterin levels could be found. In the present study neopterin levels were elevated in 5/6 patients with proven tuberculous bone infections as well. Neopterin determinations in serum were especially helpful for the drug monitoring of these patients. After a sufficient antituberculous therapy initially elevated neopterin levels decreased and remained within normal range. Persistent elevation of neopterin may be a hint for a resistance of the Mycobacteria.
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