Upregulated WTAP expression appears to both promote breast cancer growth and inhibit lymph node metastasis

Autor: Chao-Qun Wang, Chih-Hsin Tang, Yan Wang, Bi-Fei Huang, Gui-Nv Hu, Qian Wang, Jun-Kang Shao
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-05035-y
Popis: Abstract It is unclear as to whether Wilms’ tumor 1-associated protein (WTAP) promotes or suppresses breast cancer. This immunohistochemistry analysis explored levels of WTAP expression in 347 cases of breast cancer and analyzed the relationship between WTAP expression and the clinicopathological characteristics and prognosis of breast cancer patients. The rate of high WTAP expression was significantly higher in breast cancer tissue than in adjacent normal breast tissue (37.5% vs 0.0%; P
Databáze: Directory of Open Access Journals
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