Primary granulosa cell tumor of cerebellum: A rare case report

Autor: Sunil Rauniyar, Zhigang Shen, Lei Wang, Jia Gu, Mei Pengjin, Rutong Yu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Interdisciplinary Neurosurgery, Vol 23, Iss , Pp 100992- (2021)
Druh dokumentu: article
ISSN: 2214-7519
DOI: 10.1016/j.inat.2020.100992
Popis: Granulosa cell tumors (GCTs) accounts 70% of all sex cord stromal tumors, of which adult types constitutes 95%. In rare cases, Primary extraovarian GCTs can occur and is supposed to arise from mesenchymal tissue along the embryonic genital ridge. One such rare case was encountered in a 71 year-old-widow-female who was admitted with the complain of dizziness and walking instability for 10 days. MR enhancement revealed the right cerebellar hemisphere with abnormal mass about 39*42*38 mm. The patient underwent complete removal of tumor by right occipital paramedian approach. IHC results were positive for Calretinin, CD99, Vimentin, PgR, Ki67 while negative for EMA, CKpan. As, she had history of hysterectomy 45yrs ago for “Myoma of Uterus” with no pathological evidence of GCTs, the tumor was diagnosed as AGCT. This case is presented as an unusual case and is the first case to be reported in cerebellum.
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