Small molecule electro-optical binding assay using nanopores

Autor: Shenglin Cai, Jasmine Y. Y. Sze, Aleksandar P. Ivanov, Joshua B. Edel
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-09476-4
Popis: Nanopore detection of small molecules can be improved using molecular carriers, but separating a small analyte from the carrier signal can be challenging. Here the authors address this challenge using simultaneous electrical and optical readout in nanopore sensing to detect small molecules and quantify binding affinities.
Databáze: Directory of Open Access Journals