Recurrent somatic mutations as predictors of immunotherapy response

Autor: Zoran Z. Gajic, Aditya Deshpande, Mateusz Legut, Marcin Imieliński, Neville E. Sanjana
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-31055-3
Popis: Few genetic biomarkers are known for cancer immunotherapy. Here the authors identify recurrently-mutated genes and pathways associated with treatment response and develop a classifier using tumour whole exome sequencing and clinical features.
Databáze: Directory of Open Access Journals