Secondary Hemophagocytic Syndrome Associated with Richter’s Transformation in Chronic Lymphocytic Leukemia

Autor: Nura El-Haj, Wilson I. Gonsalves, Vinay Gupta, Jacob P. Smeltzer, Sameer A. Parikh, Preet P. Singh, Naseema Gangat
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Case Reports in Hematology, Vol 2014 (2014)
Druh dokumentu: article
ISSN: 2090-6560
2090-6579
DOI: 10.1155/2014/287479
Popis: Hemophagocytic syndrome (HPS) is an extremely rare condition arising from the overactivation of one’s own immune system. It results in excessive inflammation and tissue destruction. Prompt initiation of treatment is warranted in either scenario in order to decrease mortality. Most cases are triggered by infectious agents, malignancy, or drugs. We describe the first case of a CLL patient presenting with HPS due to acquisition of EBV-related large cell lymphoma in the setting of profound immunodeficiency.
Databáze: Directory of Open Access Journals