| Autor: |
Ying-Chun Chien, Chin-Hao Chang, Chun-Kai Huang, Yung-Hsuan Chen, Chia-Jung Liu, Chung-Yu Chen, Ping-Huai Wang, Chin-Chung Shu, Lu-Cheng Kuo, Jann-Yuan Wang, Shih-Chi Ku, Hao-Chien Wang, Chong-Jen Yu |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Journal of Microbiology, Immunology and Infection, Vol 57, Iss 2, Pp 328-336 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1684-1182 |
| DOI: |
10.1016/j.jmii.2023.12.009 |
| Popis: |
Background: This study investigates the impact of nontuberculous mycobacterial lung disease (NTM-LD) on mortality and mechanical ventilation use in critically ill patients. Methods: We enrolled patients with NTM-LD or tuberculosis (TB) in intensive care units (ICU) and analysed their association with 30-day mortality and with mechanical ventilator-free survival (VFS) at 30 days after ICU admission. Results: A total of 5996 ICU-admitted patients were included, of which 541 (9.0 %) had TB and 173 (2.9 %) had NTM-LD. The overall 30-day mortality was 22.2 %. The patients with NTM-LD had an adjusted hazard ratio (aHR) of 1.49 (95 % CI, 1.06–2.05), and TB patients had an aHR of 2.33 (95 % CI, 1.68–3.24), compared to ICU patients with negative sputum mycobacterial culture by multivariable Cox proportional hazard (PH) regression. The aHR of age |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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