Concurrent Lead and Noise Exposure Effects on Testicular Tissue of Rat: An Experimental Study

Autor: Batol Masruri, Iraj Alimohammadi, Mohammad Reza Abyaz, Nargess Moghadasi, Parvaneh Yekzamani, Baharak Mohammadzadeh Asl, Nooshin Asadmasjedi, Azadeh Ashtarinezhad
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Family and Reproductive Health, Vol 16, Iss 2 (2022)
Druh dokumentu: article
ISSN: 1735-8949
1735-9392
DOI: 10.18502/jfrh.v16i2.9483
Popis: Objective: Environmental stressors such as physical and chemical factors can have a destructive testicular function. The present study aimed to determine the effect of concomitant exposure to lead and noise on testicular tissue in male rats. Materials and methods: Twenty male Wistar rats (250-300 g, 12-13wk) were divided into four groups (n=5/each): 1) Control group, 2) Lead group treated with 4 mg/kg lead acetate by gavage for 30 days, 3) Noise group exposed to 4 kHz octave band at 105 dBA for eight hrs./ day for 30 days, and 4) the exposed group to lead plus noise concurrently. The testes' weight was measured, and testes abnormalities were assessed after staining with Hematoxylin and Eosin. Results: The results showed that the weight of testes in experimental groups was significantly decreased compared with the control group (p
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