Risk factors of death in children with bacterial meningitis: a systematic review and meta-analysis
| Autor: | Ni Made Maya Purnama Wulandari, Citrawati Dyah Kencono Wungu, Prastiya Indra Gunawan |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Romanian Journal of Pediatrics, Vol 72, Iss 3, Pp 101-111 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1454-0398 2069-6175 |
| DOI: | 10.37897/RJP.2023.3.6 |
| Popis: | Background and objectives. To identify the risk factors that cause death in children with bacterial meningitis. Materials and methods. Articles were obtained through a journal literature search of observational studies using electronic databases: PubMed, Scopus, ProQuest, Science Direct, and Web of Science. The articles were systematically selected using international guidelines from the Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols. Results. A literature search identified 8746 articles. After screening, 19 studies were found that met the requirements for meta-analysis. There was a total of 6997 patients aged 1 month to 18 years who were included in the study. Factors that significantly influence the risk of death in children with bacterial meningitis in this meta-analysis are: age less than five years (pooled OR = 3,19; 95% CI, 1,03-9,89; p = 0.04), age less than three years (pooled OR = 18,77; 95% CI, 2,10-167,83; p = 0.009), decreased of consciousness (pooled OR = 4,85; 95% CI, 1,25-18,86; p = 0.02), seizure (pooled OR = 2,97; 95% CI, 1,09-8,07; p = 0,03), and bacteria Streptococcus pneumoniae compared to Haemophilus influenzae from culture of cerebrospinal fluid (pooled OR = 12,52; 95% CI, 8,95-17,52; p |
| Databáze: | Directory of Open Access Journals |
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