Is heart failure with mid range ejection fraction (HFmrEF) a distinct clinical entity or an overlap group?

Autor: Jessica Webb, Jane Draper, Lauren Fovargue, Ben Sieniewicz, Justin Gould, Simon Claridge, Carys Barton, Silapiya Smith, Kristin Tondel, Ronak Rajani, Stamatis Kapetanakis, Christopher A. Rinaldi, Theresa A. McDonagh, Reza Razavi, Gerald Carr-White
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 21, Iss , Pp 1-6 (2018)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2018.06.001
Popis: Background: The new category of heart failure (HF), Heart Failure with mid range Ejection Fraction (HFmrEF) has recently been proposed with recent publications reporting that HFmrEF represents a transitional phase. The aim of this study was to determine the prevalence and clinical characteristics of patients with HFmrEF and to establish what proportion of patients transitioned to other types of HF, and how this affected clinical outcomes. Methods and results: Patients were diagnosed with HF according to the 2016 ESC guidelines. Clinical outcomes and variables were recorded for all consecutive in-patients referred to the heart failure service. In total, 677 patients with new HF were identified; 25.6% with HFpEF, 21% with HFmrEF and 53.5% with HFrEF. While clinical characteristics and prognostic factors of HFmrEF were intermediate between HFrEF and HFpEF, HFmrEF patients had the best outcome, with higher mortality in the HFrEF population (p 0.02) and higher HF rehospitalisation rates in the HFpEF population (p
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