Are Serum Procalcitonin and Interleukin-1 Beta Suitable Markers for Diagnosis of Acute Pyelonephritis in Children?

Autor: Abolfazl Mahyar, Parviz Ayazi, Reza Ahmadi, Mohammad Mahdi Daneshi-Kohan, Hassan Jahani Hashemi, Reza Dalirani, Seyed Alireza Moshiri, Morteza Habibi, Mehdi Sahmani, Ahmad Ali Sahmani
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Prague Medical Report, Vol 115, Iss 1, Pp 16-23 (2014)
Druh dokumentu: article
ISSN: 23362936
1214-6994
2336-2936
DOI: 10.14712/23362936.2014.2
Popis: Rapid diagnosis of acute pyelonephritis is important because of its association with long-standing complications. This study was conducted to compare the reliability of serum procalcitonin (PCT) and interleukin-1 beta (IL-1β) with conventional laboratory parameters for diagnosis of acute pyelonephritis in children. Seventy nine children with urinary tract infection were divided into two groups based on the result of Tc-99m dimercaptosuccinic acid renal scan: acute pyelonephritis (n=33) and lower UTI (urinary tract infection) (n=46) groups. White blood cell (WBC) count, neutrophil count, erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP), PCT and IL-1β concentrations of both groups were measured and compared. WBC count, neutrophil count, ESR, serum CRP, PCT and IL-1β concentrations were higher in acute pyelonephritis patients than in the lower UTI group (P
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