Letter to the editor concerning the article ‘Safety of vaccines administration in hereditary fructose intolerance’

Autor: Rebeca Saborido-Fiaño, Nazareth Martinón-Torres, Vanesa Crujeiras-Martinez, Maria Luz Couce, Rosaura Leis
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 17, Iss 8, Pp 2593-2594 (2021)
Druh dokumentu: article
ISSN: 2164-5515
2164-554X
21645515
DOI: 10.1080/21645515.2021.1891816
Popis: The most important approach for the management of hereditary fructose intolerance is a strict avoidance of fructose, sucrose and sorbitol from the diet and medications. A safe threshold of 2.4 mg/kg/dose was recently established by the Instituto Superiore di Sanità of Italy for both oral and parenteral routes, thus shouldering a safe administration of a majority of vaccines in these patients. This would not include, Rotarix® pre-established oral suspension and Rotateq® vaccines, which are indeed contraindicated. Moreover, Rotarix® white powder and solvent for oral suspension would only be safely administered at a weight above 9.3 kg. Overall, these recommendations to avoid rotavirus vaccination are difficult to implement because these vaccines are given during exclusive breastfeeding, prior to fructose-containing food introduction.
Databáze: Directory of Open Access Journals