An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

Autor: MARIANA Q. MESQUITA, CRISTINA J. DIAS, SARA GAMELAS, MARGARIDA FARDILHA, MARIA G.P.M.S. NEVES, MARIA AMPARO F. FAUSTINO
Jazyk: angličtina
Předmět:
Zdroj: Anais da Academia Brasileira de Ciências, Vol 90, Iss 1 suppl 2, Pp 1101-1130
Druh dokumentu: article
ISSN: 1678-2690
0001-3765
DOI: 10.1590/0001-3765201720170800
Popis: ABSTRACT Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.
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