Dietary Oxalate Induces Urinary Nanocrystals in Humans

Autor: Parveen Kumar, Mikita Patel, Vinoy Thomas, John Knight, Ross P. Holmes, Tanecia Mitchell
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Kidney International Reports, Vol 5, Iss 7, Pp 1040-1051 (2020)
Druh dokumentu: article
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2020.04.029
Popis: Introduction: Crystalluria is thought to be associated with kidney stone formation and can occur when urine becomes supersaturated with calcium, oxalate, and phosphate. The principal method used to identify urinary crystals is microscopy, with or without a polarized light source. This method can detect crystals above 1 μm in diameter (microcrystals). However, analyses of calcium oxalate kidney stones have indicated that crystallite components in these calculi are 50–100 nm in diameter. Recent studies have suggested that nanocrystals (
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