| Autor: |
Rene Ivan Gonzalez-Fernandez, Vicente Rio-Vazquez, Jorge German Perez-Blanco, Ernesto Velarde-Reyes, Liana Portela-Hernandez, Aisel Santos-Santos, Joel Gutierrez-Gil, Jose Luis Hernandez-Caceres |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Exploration of Neuroscience, Vol 3, Iss 2, Pp 144-155 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2834-5347 |
| DOI: |
10.37349/en.2024.00041 |
| Popis: |
Aim: The aim of this paper is to discuss the main features and first outcomes of a therapeutic platform proposed to implement a public health therapeutic service for patients suffering refractory epilepsy. Methods: The proposal is a three-layer system composed by a new portable therapy device and two software applications. The therapy is transcutaneous electrical vagus nerve stimulation, known as tVNS. The primary layer is composed of tVNS devices, configured for each patient according to the instructions provided by the specialists. The middle layer is named “hospital data collector” (HDC), its main tasks are the patient enrollment, the device setup, and the database maintenance to store therapeutic parameters and session events together with the information cited previously. Each hospital center runs a HDC that is connected to a cloud application named “system cloud application (SCA)” which concentrates all the data supplied by the HDCs. Artificial intelligence methods are integrated in the SCA to predict the treatment effectiveness for every new patient based on the accumulated knowledge from the enrolled previously. Results: A version of the proposed system is running at the Institute of Neurology and Neurosurgery. The sensitivity of the therapeutic device with the proposed treatment protocol reaches 83.33% in the 18-patient pilot trial carried out. Conclusions: The proposed approach seems a useful therapeutic tool based on the pilot trial outcomes. The developed device is comfortable and suitable for the intended use. The proposed system has created the essential conditions to feed and grow a knowledge, a basic element to predict the treatment effectiveness for each new patient. It is a promising option for a refractory epilepsy therapy service. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
