| Autor: |
Rafael Simone Saia, Humberto Giusti, Fábio Luis-Silva, Karina de Jesus Bonicenha Pedroso, Maria Auxiliadora-Martins, Karen Mirna Loro Morejón, Augusto Marcussi Degiovani, Márcia Regina Cadelca, Anibal Basile-Filho |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 113, Iss , Pp 82-86 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2021.09.051 |
| Popis: |
ABSTRACT: Objectives: SARS-CoV-2 exhibits tropism for the gastrointestinal tract; however, lesions in enterocytes and their correlation with disease severity and patient prognosis are still unknown. Methods: SARS-CoV-2 patients were enrolled in 5 medical centres in São Paulo, Brazil and their clinical characteristics and laboratory findings recorded. At admission, day 7 and day 14 of hospitalisation, plasma and urine samples were collected, and cytokine levels and intestinal fatty acid-binding protein (I-FABP) concentrations measured. Results: COVID-19 patients displayed ≈48-, 74- and 125-fold increased urinary I-FABP levels at admission (n=283; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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