| Autor: |
Louis Grandjean, Tomotada Iwamoto, Anna Lithgow, Robert H Gilman, Kentaro Arikawa, Noriko Nakanishi, Laura Martin, Edith Castillo, Valentina Alarcon, Jorge Coronel, Walter Solano, Minoo Aminian, Claudia Guezala, Nalin Rastogi, David Couvin, Patricia Sheen, Mirko Zimic, David A J Moore |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 10, Iss 5, p e0126271 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0126271 |
| Popis: |
The comparison of Mycobacterium tuberculosis bacterial genotypes with phenotypic, demographic, geospatial and clinical data improves our understanding of how strain lineage influences the development of drug-resistance and the spread of tuberculosis.To investigate the association of Mycobacterium tuberculosis bacterial genotype with drug-resistance. Drug susceptibility testing together with genotyping using both 15-loci MIRU-typing and spoligotyping, was performed on 2,139 culture positive isolates, each from a different patient in Lima, Peru. Demographic, geospatial and socio-economic data were collected using questionnaires, global positioning equipment and the latest national census.The Latin American Mediterranean (LAM) clade (OR 2.4, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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