Antimicrobial Resistance Patterns in Clinically Significant Isolates from Medical Wards of a Tertiary Care Hospital in North India

Autor: Venkatesh Sudharsan Vaithiyam, Neha Rastogi, Piyush Ranjan, Niranjan Mahishi, Arti Kapil, Sada Nand Dwivedi, Manish Soneja, Naveet Wig, Ashutosh Biswas
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Laboratory Physicians, Vol 12, Iss 03, Pp 196-202 (2020)
Druh dokumentu: article
ISSN: 0974-2727
0974-7826
DOI: 10.1055/s-0040-1721161
Popis: Background The global burden of infections due to multidrug-resistant organism (MDRO) has a significant impact on patients’ morbidity and mortality along with increased healthcare expenditure. Aim This article estimates the prevalence of MDRO and the spectrum of clinical infectious syndromes caused by these organisms in medical wards of a tertiary care hospital in India. Design and Methods A cross-sectional observational study was performed among patients admitted in medicine wards diagnosed with the various infectious syndromes and one or more clinically significant positive culture at a tertiary care hospital in North India over a period of 18 months. Results Out of 323 clinically significant microbiological culture isolates from 229 patients included in the study, 86 (27%) isolates showed multidrug resistance (MDR) pattern, 197 (61%) isolates showed possible extremely drug-resistance pattern, and only 40 (12%) isolates showed nonmultidrug-resistance pattern of antibiogram. Conclusion The prevalence of MRDOs is high in clinically significant culture isolates from medicine wards in India. This emphasizes the importance of appropriate antibiotic usage and implementation of antibiotic stewardship programs in this part of the world.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje