Role of m6A writers, erasers and readers in cancer

Autor:	Zhen Fang, Wentong Mei, Chang Qu, Jiongdi Lu, Liang Shang, Feng Cao, Fei Li
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	N6-methyladenosine (m6A) Cancer Writers Erasers Readers Diseases of the blood and blood-forming organs RC633-647.5 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-20 (2022)
Druh dokumentu:	article
ISSN:	2162-3619
DOI:	10.1186/s40164-022-00298-7
Popis:	Abstract The N(6)-methyladenosine (m6A) modification is the most pervasive modification of human RNAs. In recent years, an increasing number of studies have suggested that m6A likely plays important roles in cancers. Many studies have demonstrated that m6A is involved in the biological functions of cancer cells, such as proliferation, invasion, metastasis, and drug resistance. In addition, m6A is closely related to the prognosis of cancer patients. In this review, we highlight recent advances in understanding the function of m6A in various cancers. We emphasize the importance of m6A to cancer progression and look forward to describe future research directions.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/39e5e414cd50459fa4625d4125df7be5 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.