Infliximab in the treatment of Budd-Chiari syndrome in Behçet’s disease
| Autor: | L.B. Santos, J. Rigueira, A.P. Vilas |
|---|---|
| Jazyk: | English<br />Italian |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Reumatismo, Vol 71, Iss 3 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0048-7449 2240-2683 |
| DOI: | 10.4081/reumatismo.2019.1153 |
| Popis: | Behçet’s disease is a chronic autoinflammatory disorder that usually presents with recurrent oral and genital ulcers, uveitis, skin lesions and arthritis. Any organ, however, can be involved and in a subgroup of patients the large vascular lesions are the predominant feature (vasculo-Behçet disease). We report a case of a 27-yearold man with Behçet’s disease who developed Budd-Chiari syndrome while on immunosuppressive therapy. Infliximab resulted in a rapid and total clinical remission. Literature data have shown that antitumor necrosis factor alpha (anti-TNF-α) agents including infliximab can suppress disease activity but there is no long-term experience on tapering and/or discontinuation of treatment under clinical remission. Our case supports the use of infliximab in vasculo-Behçet patients. |
| Databáze: | Directory of Open Access Journals |
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