Molecular genetic features of cutaneous T-cell lymphomas development on example of mycosis fungoides and Sezary syndrome

Autor:	M. B. Khadzhieva, E. S. Zakharova, E. V. Kalinina, D. S. Abramov, A. G. Rumyantsev, S. S. Larin
Jazyk:	ruština
Rok vydání:	2022
Předmět:	cutaneous t-cell lymphoma mycosis fungoides sezary syndrome t-cell clonality Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Онкогематология, Vol 17, Iss 1, Pp 65-74 (2022)
Druh dokumentu:	article
ISSN:	1818-8346 2413-4023
DOI:	10.17650/1818-8346-2022-17-1-65-74
Popis:	Cutaneous T-cell lymphomas are a heterogeneous group of T-cell lymphoproliferative diseases affecting the skin. Mycosis fungoides and Sezary syndrome are the most studied variants of them. The literature review includes the latest published data on the pathological processes development in mycosis fungoides and Sezary syndrome and the diagnosis of these diseases. The genomic instability features in cutaneous T-cell lymphomas are described, the existing hypotheses of the origin of these diseases are considered based on the results of T-cell receptor repertoire studying.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/39d4740d3ea147b4afc35b8eab9b6869 Zobrazit plný text záznamu View record in DOAJ