Extracorporeal cytokine removal in chimeric antigen receptor T-cell therapy associated cytokine release syndrome in patient with acute lymphoblastic leukemia. Case report

Autor: Antonina E. Shchekina, Gennadii M. Galstyan, Olga A. Gavrilina, Natalia M. Arapova, Svetlana Iu. Bronyakina, Ekaterina S. Kotova, Vera V. Troitskaya, Elena N. Parovichnikova, Mikhail A. Maschan, Valerii G. Savchenko
Jazyk: ruština
Rok vydání: 2021
Předmět:
Zdroj: Терапевтический архив, Vol 93, Iss 7, Pp 811-817 (2021)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
00403660
DOI: 10.26442/00403660.2021.07.200931
Popis: Сytokine release syndrome is the common complication of CAR-T therapy. We report a case of patient with B-cell acute lymphoblastic leukemia developing сytokine release syndrome with shock and multiple organ failure and requiring cytokine removal and hemodiafiltration. Remission of the disease was achieved after CAR-T therapy.
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