| Autor: |
George Felipe Bezerra Darce, Fabio Ferrari Makdissi, Sabrina de Mello Ando, Gilton Marques Fonseca, Jaime Arthur Pirola Kruger, Fabricio Ferreira Coelho, Manoel de Souza Rocha, Paulo Herman |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
ABCD: Arquivos Brasileiros de Cirurgia Digestiva, Vol 36 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
0102-6720 |
| DOI: |
10.1590/0102-672020230045e1763 |
| Popis: |
ABSTRACT BACKGROUND: Hepatosplenic schistosomiasis is an endemic disease prevalent in tropical countries and is associated with a high incidence of portal vein thrombosis. Inflammatory changes caused by both parasitic infection and portal thrombosis can lead to the development of chronic liver disease with potential carcinogenesis. AIMS: To assess the incidence of portal vein thrombosis and hepatocellular carcinoma in patients with schistosomiasis during long-term follow-up. METHODS: A retrospective study was conducted involving patients with schistosomiasis followed up at our institution between 1990 and 2021. RESULTS: A total of 126 patients with schistosomiasis were evaluated in the study. The mean follow-up time was 16 years (range 5–31). Of the total, 73 (57.9%) patients presented portal vein thrombosis during follow-up. Six (8.1%) of them were diagnosed with hepatocellular carcinoma, all with portal vein thrombosis diagnosed more than ten years before. CONCLUSIONS: The incidence of hepatocellular carcinoma in patients with schistosomiasis and chronic portal vein thrombosis highlights the importance of a systematic long-term follow-up in this group of patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
