Sequential Activations of ChREBP and SREBP1 Signals Regulate the High-Carbohydrate Diet-Induced Hepatic Lipid Deposition in Gibel Carp (Carassius gibelio)

Autor: Yulong Gong, Longwei Xi, Yulong Liu, Qisheng Lu, Zhimin Zhang, Haokun Liu, Junyan Jin, Yunxia Yang, Xiaoming Zhu, Shouqi Xie, Dong Han
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Aquaculture Nutrition, Vol 2023 (2023)
Druh dokumentu: article
ISSN: 1365-2095
DOI: 10.1155/2023/6672985
Popis: The present study investigated the sequential regulation signals of high-carbohydrate diet (HCD)-induced hepatic lipid deposition in gibel carp (Carassius gibelio). Two isonitrogenous and isolipidic diets, containing 25% (normal carbohydrate diet, NCD) and 45% (HCD) corn starch, were formulated to feed gibel carp (14.82 ± 0.04 g) for 8 weeks. The experimental fish were sampled at 2nd, 4th, 6th, and 8th week. In HCD group, the hyperlipidemia and significant hepatic lipid deposition (oil red O area and triglyceride content) was found at 4th, 6th, and 8th week, while the significant hyperglycemia was found at 2nd, 4th, and 8th week, compared to NCD group (P
Databáze: Directory of Open Access Journals
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