| Autor: |
Yue Wang, Ziting Zhang, Min Du, Xu Ji, Xiaodan Liu, Chunfang Zhao, Xunsheng Pang, Erhui Jin, Aiyou Wen, Shenghe Li, Feng Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Immunology, Vol 15 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1664-3224 |
| DOI: |
10.3389/fimmu.2024.1460127 |
| Popis: |
IntroductionEnterotoxigenic Escherichia coli (ETEC) is the main diarrhea-causing pathogen in children and young animals and has become a global health concern. Berberine is a type of “medicine and food homology” and has a long history of use in China, particularly in treating gastrointestinal disorders and bacterial diarrhea.MethodsIn this study, we explored the effects of berberine on growth performance, intestinal inflammation, oxidative damage, and intestinal microbiota in a weaned piglet model of ETEC infection. Twenty-four piglets were randomly divided into four groups—a control group (fed a basal diet [BD] and infused with saline), a BD+ETEC group (fed a basal diet and infused with ETEC), a LB+ETEC group (fed a basal diet with 0.05% berberine and infused with ETEC infection), and a HB+ETEC group (fed a basal diet with 0.1% berberine and infused with ETEC).ResultsBerberine significantly improved the final body weight (BW), average daily gain (ADG), and average daily feed intake (ADFI) (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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