Procalcitonin, C-Reactive Protein, Albumin, and Blood Cultures as Early Markers of Sepsis Diagnosis or Predictors of Outcome: A Prospective Analysis

Autor: Ana Cristina Schmidt de Oliveira-Netto, Luis G Morello, Libera M Dalla-Costa, Ricardo R Petterle, Rafael M Fontana, Danieli Conte, Luciane A Pereira, Sonia M Raboni
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Clinical Pathology, Vol 12 (2019)
Druh dokumentu: article
ISSN: 2632-010X
2632010X
DOI: 10.1177/2632010X19847673
Popis: Purpose: Sepsis is a condition with high mortality rates and its diagnosis remains a challenge. We assessed epidemiological, clinical data, multiple biomarker profiles, and blood culture with respect to sepsis diagnosis and predictors of outcome. Methods: In total, 183 patients who were suspected of having sepsis and underwent blood culture collection were followed up for 7 days. Sepsis-related Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation (APACHE) II scores were calculated daily; biomarkers and blood culture test results were evaluated. Results: In total, 78 (43%) had sepsis, 50 (27%) had septic shock, and 55 (30%) had no sepsis. Blood culture was positive in 28% and 42% of the sepsis and septic shock groups, respectively ( P
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