Factors influencing in-hospital mortality in cancer patients with COVID-19: A retrospective survival analysis

Autor: Sandra Brigitte Amado-Garzón, Luisana Molina-Pimienta, Juan Manuel Vásquez-Jiménez, Karen Lizeth Álvarez-Raigoza, Mauricio Manrique-Samer, Carlos E Lombo-Moreno, Alejandra Cañas-Arboleda
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: SAGE Open Medicine, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2050-3121
20503121
DOI: 10.1177/20503121241295852
Popis: Objective: The aim of this study was to evaluate survival in patients with COVID-19 and cancer, and to find factors associated with early mortality. Methods: Retrospective cohort derived from a registry of a referral center in Bogotá. Survival was analyzed according to the type of neoplasm using Kaplan–Meier method. A cox regression was performed to look for factors associated to higher risk of death. Results: Two hundred fifty-four patients were included with cancer and COVID-19, most of whom were women (median age 68 years; range 19–97). Cardiovascular comorbidities were frequent. Patients with hematologic neoplasms had higher survival than those with solid neoplasms (log-rank test, p = 0.024). C-reactive protein levels (hazard ratio 1.02; 95% confidence interval 1.00–1.03, p = 0.025), Charlson’s comorbidity index (hazard ratio 1.15; 95% confidence interval 1.06–1.26, p = 0.004) and respiratory failure (hazard ratio 4.83; 95% confidence interval 2.47–9.44, p =
Databáze: Directory of Open Access Journals