Factors influencing in-hospital mortality in cancer patients with COVID-19: A retrospective survival analysis
Autor: | Sandra Brigitte Amado-Garzón, Luisana Molina-Pimienta, Juan Manuel Vásquez-Jiménez, Karen Lizeth Álvarez-Raigoza, Mauricio Manrique-Samer, Carlos E Lombo-Moreno, Alejandra Cañas-Arboleda |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | SAGE Open Medicine, Vol 12 (2024) |
Druh dokumentu: | article |
ISSN: | 2050-3121 20503121 |
DOI: | 10.1177/20503121241295852 |
Popis: | Objective: The aim of this study was to evaluate survival in patients with COVID-19 and cancer, and to find factors associated with early mortality. Methods: Retrospective cohort derived from a registry of a referral center in Bogotá. Survival was analyzed according to the type of neoplasm using Kaplan–Meier method. A cox regression was performed to look for factors associated to higher risk of death. Results: Two hundred fifty-four patients were included with cancer and COVID-19, most of whom were women (median age 68 years; range 19–97). Cardiovascular comorbidities were frequent. Patients with hematologic neoplasms had higher survival than those with solid neoplasms (log-rank test, p = 0.024). C-reactive protein levels (hazard ratio 1.02; 95% confidence interval 1.00–1.03, p = 0.025), Charlson’s comorbidity index (hazard ratio 1.15; 95% confidence interval 1.06–1.26, p = 0.004) and respiratory failure (hazard ratio 4.83; 95% confidence interval 2.47–9.44, p = |
Databáze: | Directory of Open Access Journals |
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